Greek researchers studied the effects of consuming a fortified juice containing 2,000 IU of vitamin D and probiotic strains for 8 weeks Bacillus casei laticacei With Mr. Shirota Lactocei Bacillus rhamnosusGG(10)8CFU/mL) influence cardiometabolic risk factors in overweight and obese adults.
“Fortified OJ leads to weight loss, reduced energy/macronutrient consumption, improved lipid profile, and increased insulin sensitivity in people on a Westernized diet, thus potentially contributing to cardiometabolic risk.” “We show significant benefits,” the researchers reported.
Research published in journals nutrientsis part of the FunJuice project, which is funded by the EU Regional Development Fund and Greek National Resources.
innovative dietary interventions
To combat obesity, research is investigating innovative dietary interventions that leverage the combined effects of bioactive substances such as vitamin D and probiotics.
“Vitamin D3 has emerged as a focal point in enhancing insulin sensitivity, regulating lipid profiles, and exerting anti-inflammatory effects. [while] “Probiotics have been recognized for their ability to modulate the gut microbiota, systemic inflammation, and lipid metabolism,” the Greek researchers wrote.
A 2020 review highlights that the synergistic effects of taking vitamin D and probiotics together are more effective than either ingredient alone in ameliorating chronic disease markers and improving metabolic health. it was done.
However, the role of fruit juices in health is controversial. Fruit juices can increase blood sugar levels after meals, so it is recommended to limit your intake. Nevertheless, there is evidence that moderate daily consumption does not worsen the risk of chronic disease and may have vascular, anti-inflammatory, and antioxidant benefits.
research content
In a randomized, double-blind, parallel-controlled trial, 53 high-risk adults were randomly assigned to two groups. For 8 weeks, all subjects drank 250 ml of OJ (Aspis SA Hellenic Juice Industry, Argos Corinthos, Greece) 30 minutes before lunch every day. One group’s OJ was rich in vitamin D3 and probiotics. Addition of vitamin D and probiotics did not change the sensory properties of OJ.
Metabolic and inflammatory markers and blood pressure were measured at the beginning and end of the study.
This study used a 3-day food diary to assess compliance and estimated vitamin D intake from baseline, 4-week, and 8-week dietary records. Sun exposure was also assessed by questionnaire to assess the extent to which it affects the skin synthesis of vitamin D.
Findings showed that concentrated OJ led to weight loss, reduced energy/macronutrient consumption, improved lipid profile, and increased insulin sensitivity after 8 weeks, suggesting potential benefits on cardiometabolic risk. Masu. These benefits were recorded without changes in triglycerides, inflammation, or central blood pressure.
“The results of this study highlight the potential of OJ, which is rich in vitamin D3 and probiotics (Bacillus casei laticaceiWith Mr. Shirota Lactocei Bacillus rhamnosusGG) is a functional food that positively impacts metabolic health markers in adults at high cardiometabolic risk,” the researchers concluded, adding that functional foods can be incorporated into personalized nutrition to address metabolic dysfunction. He pointed out the possibility of mitigation.
As study limitations, the researchers noted that the intervention period was short and the study design did not include separate vitamin D3 or probiotic groups, which precluded evaluation of synergistic effects.
In this study, despite the randomized control method, differences between groups were also observed for several metabolic markers.
“There are also individual differences in response to interventions, and further investigation is needed, taking into account the influence of factors such as gut microbiota composition,” the researchers wrote.
journal: nutrients
doi: 10.3390/nu16091331
“Two months of orange juice enriched with vitamin D3 and probiotics reduces weight, insulin resistance, blood lipids, and arterial blood pressure in high cardiometabolic risk patients on a Western diet: Results of a randomized clinical trial.”
Author: E. Papakonstantinou et al.
