THURSDAY, June 6, 2024 (HealthDay News) — A positive correlation exists between diet-induced inflammation and heart failure biomarkers, according to a study published online June 5. ProSone.
Ma Tengzhi and his colleagues from the First Affiliated Hospital of Xi’an Jiaotong University in China used data from the National Health and Nutrition Survey (1999 to 2004, 10,766 people) to investigate the association between diet-induced inflammation (measured by the dietary inflammatory index) and obesity. [DII]) and heart failure (measured by N-terminal pro-B-type natriuretic peptide). [NT-proBNP]).
The researchers found that in people without heart failure, each unit increase in DII was significantly associated with higher NT-proBNP levels when adjusting for demographic factors (8.57 pg/mL) and further adjusting for health variables (5.54 pg/mL). In people with a history of heart failure, there was a trend for higher NT-proBNP levels in the second and third quartiles of DII compared with the lowest quartile (717.06 pg/mL and 855.49 pg/mL, respectively). There were also significant interactions by age (<50 years: β = 3.63; 50-75 years: β = 18.4; ≥75 years: β = 56.09), sex (males: β = 17.82; females: β = 7.43), hypertension (β = 25.73), and diabetes (β = 38.94).
“In this study, we found a positive correlation between DII and NT-proBNP levels, suggesting a strong association between a pro-inflammatory diet and increased heart failure biomarkers, with implications for dietary modification in cardiovascular risk management,” the authors conclude.
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