Highlights:
- By week 16, dermal density had increased by approximately 16% in both treatment groups.
- Rough skin and wrinkles also decreased by more than 9% and 13%, respectively, in both groups.
Studies have shown that supplementation with a formula containing collagen and vitamin C has improved dermal density, texture, and signs of aging such as wrinkles.
“Increased awareness of the link between nutrition and skin health, and all aspects from beauty and wellness to the ageing process, has led to increased interest in dietary interventions and supplements to maintain a youthful appearance.” Katya MitecPhD, “Collagen supplements are becoming increasingly popular due to their potential to stimulate collagen synthesis,” he and his colleagues wrote, as well as leader of the Cosmetics Research Group at the Swiss Nutrition Institute and associate professor and vice dean at the School of Advanced Applied Sciences. [extracellular matrix] Ingredients such as collagen [hyaluronic acid]and inhibit their degradation [matrix metalloproteinases]It is an ingredient that can be expected to prevent skin aging.
In this randomized, placebo-controlled, double-blind study, the authors investigated the effects of daily dietary supplementation with hydrolyzed collagen and vitamin C on skin aging.
Eighty-seven women aged between 40 and 65 years were divided equally into three groups. In the first group, 28 patients received the investigational product (CPHA product) consisting of 5 g collagen, 80 mg vitamin C, and 30 mg hyaluronic acid. In the second group, 30 patients received the investigational product (CP) consisting of 5 g collagen and 80 mg vitamin C, and the third group, consisting of 29 subjects, received a placebo.
Patients continued daily treatment for 16 weeks. Researchers performed periodic examinations at baseline, 8 weeks, and 16 weeks to assess dermal density, thickness, skin hydration, and viscoelasticity, as well as skin roughness and wrinkling at baseline and 16 weeks.
By week 16, dermal density increased by 16.3% in the CP group and 16% in the CPHA group compared to placebo, with no significant differences between treatment groups (P both < .001).
By week 16, skin roughness had increased in the placebo group, but decreased by 9.6% and 9.9% in the CP and CPHA groups, respectively (P Both < .001.) Supplementation also improved wrinkles, with the amount of wrinkles decreasing by 13.8% and 13.9% in the CP and CPHA groups, respectively, compared to the placebo group (P both < .001).
However, no significant improvements were observed in skin elasticity or hydration. Furthermore, the authors reported that adding hyaluronic acid to the supplement did not seem to improve results.
“Addition of HA to collagen did not show any superior effect on any of the skin parameters evaluated, therefore we cannot confirm the ability of HA to further improve the effects observed with collagen supplementation,” the researchers wrote.
Overall, the authors concluded that collagen and vitamin C supplementation improved signs of skin aging, including dermal density, skin roughness, and wrinkle severity.
Sources/Disclosures
Collapse
Disclosure: The authors report no relevant financial disclosures. This work was funded by the Slovenian Research and Innovation Agency’s research program P3-0395: Nutrition and Public Health and by Tosla doo.
