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This article is sponsored content by Daniel Dayton
While aging is a natural process, the pursuit of longevity and vitality has prompted scientific research into various supplements that may slow or even reverse the aging process. In recent years, several compounds have garnered attention for their potential anti-aging effects. Here, we take a closer look at some of the most promising anti-aging supplements and explore their effects and how they work.
1. Nicotinamide Mononucleotide (NMN)
NMN is a derivative of Vitamin B3 and a precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme essential for cellular energy production and metabolism. NAD+ levels decline with age, leading to decreased cellular function and increased susceptibility to age-related diseases. Supplementing with NMN increases NAD+ levels, enhancing energy production, improving DNA repair, and promoting cellular health.
Recent studies have also found that nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation, including transcriptional footprinting of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. (PMID: 32056076)
Many researchers and scientists, including Dr. David Sinclair, Chair of the Department of Genetics at Harvard University, take NMN daily as part of a longevity strategy and praise its effectiveness.
2. Resveratrol
Resveratrol is a polyphenol found in red wine, grapes, and certain berries. It is known for its antioxidant properties and ability to activate sirtuins, proteins that play an important role in cellular health and longevity.
advantage:
- Acts as a powerful antioxidant
- Activating Sirtuins to Promote Cellular Health
- Supports Cardiovascular Health
- May reduce inflammation and oxidative stress
3. Quercetin
Quercetin is a flavonoid found in many fruits, vegetables, and grains. It has powerful antioxidant and anti-inflammatory properties and is known to support immune function and overall health.
advantage:
- Provides Antioxidant Protection
- Reduces inflammation
- Supports Immune Health
- May improve cardiovascular health
4. Fisetin
Fisetin is another flavonoid found in fruits and vegetables such as strawberries, apples, and onions. It has been shown to have anti-inflammatory, antioxidant, and senolytic properties (the ability to selectively eliminate senescent cells).
advantage:
- Acts as a powerful antioxidant
- Reduces inflammation
- Promotes the removal of senescent cells
- Supports cognitive function
5. Trimethylglycine (TMG)
TMG, also known as betaine, is a compound derived from choline that is involved in methylation, a process important in DNA repair, detoxification, and regulating gene expression.
advantage:
- Supports DNA repair and methylation
- Aids in detoxification
- Promotes cardiovascular health
- Improves liver function
6. Spermidine
Spermidine is a polyamine found in a variety of foods, including wheat germ, soy, and aged cheese. It is known for its ability to promote autophagy, a cellular process that removes damaged components and promotes cell renewal.
advantage:
- Promotes autophagy and cell renewal
- Supports Cardiovascular Health
- May boost cognitive function
- Provides anti-inflammatory effects
7. Epigallocatechin gallate (EGCG)
EGCG is a catechin found in green tea that is a powerful antioxidant known for its ability to support metabolic health and prevent cellular damage.
advantage:
- Provides Powerful Antioxidant Protection
- Supports Metabolic Health
- May reduce inflammation
- Promotes cardiovascular health
8. Astragalus
Astragalus is a traditional Chinese herb known for its immune-boosting and anti-aging properties. It contains compounds such as cycloastragenol and astragaloside IV, which are thought to help protect telomeres, the protective caps at the ends of chromosomes.
advantage:
- Supports Immune Health
- Promotes telomere protection
- Has antioxidant and anti-inflammatory properties
- Supports Cardiovascular Health
9. Piperine
Piperine is an alkaloid found in black pepper. It is known for its ability to increase the bioavailability of various nutrients and compounds, making it a valuable addition to many supplement regimens.
advantage:
- Increases nutrient absorption
- Improves the bioavailability of supplements
- Has anti-inflammatory and antioxidant properties
- Supports Digestive Health
10. L-Theanine
L-theanine is an amino acid found in tea leaves. It has a calming effect and is known to promote relaxation without causing drowsiness. It also supports cognitive function and reduces stress.
advantage:
- Promotes relaxation and reduces stress
- Supports cognitive function
- Enhances mood and mental clarity
- Provides Antioxidant Protection
Conclusion
As the search for the fountain of youth continues, these supplements offer promising benefits that can help slow the aging process and promote overall health and vitality. One scientifically proven anti-aging supplement is AEON, which contains all of the ingredients we’ve talked about today in one capsule.
All of these ingredients are in liposomal form. Additionally, piperine has been shown to increase the absorption of antioxidants such as resveratrol by up to 1500% (Study: PMID21714124). This makes AEON a great choice for anyone looking for a powerful all-in-one longevity supplement.
Perpetua Life Biotech, the company that manufactures AEON, is also a full-fledged research and development company with a medical board of outstanding MDs and PhDs from around the world. All of their products are in-house developed, sourced and manufactured in the United States. All facilities are also NSF/GMP audited and FDA registered to ensure consistent quality.
If you decide to give AEON a try, use coupon code JOURNAL to get an extra 10% off your order at Perpetua.Life.
