Article provided by: Dr. Joel Kahn, MDHe is a clinical professor at Wayne State University School of Medicine, a world-class cardiologist, best-selling author, lecturer, and a leading authority on plant-based nutrition and holistic care.
Dr. Khan will be one of the featured speakers at A4M’s 32nd Annual Spring Conference, May 3-5, 2024 in West Palm Beach, Florida. He will participate in a session on Nutrition for Health: Optimizing Nutrition, Decoding Metabolic Malfunctions. , elucidation of genetic influences. For more information, please visit: go.a4m.com
One of the most interesting stories in the pharmaceutical industry is the development of Viagra (sildenafil) as a heart drug that had the unexpected but welcome side effect of being an effective treatment for erectile dysfunction (ED). Viagra and Cialis became blockbuster drugs, and both are now available as generic drugs.
Over the years, these drugs have expanded in use for cardiopulmonary and prostate indications.
recently, report They suggest that they may lower the risk of dementia.
More benefits? Two new studies suggest that these drugs may have anti-aging effects.
research 1
retrospective observation cohort study The study was conducted in a large commercial insurance claims database in the United States among men diagnosed with ED without previous cardiac disease within 1 year. The tadalafil group (n = 8156) had at least one application for tadalafil. There were no claims for ED medications in the non-tadalafil group (n = 21,012).
The adjusted incidence of cardiac adverse events was 19% lower in men exposed to tadalafil compared with unexposed men. Exposure to tadalafil was associated with lower adjusted rates of coronary revascularization, unstable angina, and cardiovascular-related mortality. The overall mortality rate was 44% lower in men exposed to tadalafil. Men with the highest exposure to tadalafil had the lowest rates of cardiac events.
research 2
The UK Biobank has recorded prescription drug and mortality data for more than 500,000 patients for over 40 years.a new research investigated the impact of the top 406 prescribed drugs on overall mortality in the general UK population.
Several drugs appear to have beneficial effects on longevity, especially sildenafil (Viagra) and tadalafil (Cialis), as well as atorvastatin, naproxen, and estradiol.
conclusion
These two database studies hypothesize that men who use ED drugs like Cialis and Viagra not only have lower rates of dementia, but may also have fewer cardiac events and live longer lives. I am. These are very provocative concepts. These drugs are generally cheap and safe.
Perhaps there will be randomized studies on longevity. We need more data. For now, it’s reassuring that new benefits for both brain health and heart health have been reported. In my clinic, tadalafil is a daily routine prescription.
It is clear that data on the use of these or similar drugs in women and evaluation of their benefits to the brain and heart are desperately needed.
