FRIDAY, May 17, 2024 (HealthDay News) — Vitamin D deficiency is associated with increased risk of cardiovascular mortality and chronic kidney disease (CKD) progression in patients with early-stage disease, a study published online May 11 says. The results of the study were published in the edition. Endocrinological Research Journal.
Yanhong Lin and colleagues at Southern Medical University in Guangzhou, China, have found that 25-hydroxyvitamin D (25[OH]D) Deficiencies in cardiovascular mortality and renal outcomes in patients with early-stage CKD. The analysis included 9,229 adult patients with CKD (stages 1-3) from 19 medical centers across China (January 2000 to May 2021).
Researchers found that patients with 25(OH)D ≥20 ng/mL had a significantly higher risk of cardiovascular mortality (hazard ratio 1.90) and CKD progression (hazard ratio 2.20) and a lower annual mortality rate. I found it to be expensive. Patients with serum 25(OH)D <10 ng/mL have a decreased estimated glomerular filtration rate (estimated, -7.87 percent per year).
“In conclusion, 25(OH)D deficiency was common in patients with early-stage CKD,” the authors wrote. “Vitamin D status should be carefully monitored in patients with early CKD. To determine whether timely vitamin D supplementation can prevent cardiovascular events and loss of renal function in patients with early CKD and 25(OH) Well-designed, randomized clinical trials are needed for ‘D deficiency. ”
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