An anti-aging drug for older dogs is currently in clinical trials. If it works as expected, treatments may be developed that not only extend the lifespan of your pet, but also extend your life someday.
Things necessary: Large dogs tend to have shorter lifespans than small dogs. For example, a Chihuahua is expected to live 15 to 17 years, while a Great Dane tends to only live 8 to 10 years.
Biotechnology company Royal is developing an injectable drug, LOY-001, that aims to not only extend the lifespan of large breed dogs, but also keep them healthy for longer. announced that they had cleared a milestone. F.D.A.
This new anti-aging drug is being tested on older dogs weighing just 14 pounds.
“Stay”: Royal has now begun the STAY study, which involves daily administration of an anti-aging drug called LOY-002 to older dogs. The pill is designed to “improve metabolic fitness” in a way that Royal hopes will increase the number of years the dog lives in good health.
This drug is not just for large dogs. The study is enrolling older dogs weighing as much as 14 pounds, meaning all breeds except the smallest can participate.
detail: To participate in the STAY study, in addition to weighing at least 14 pounds, dogs must be at least 10 years old and live near one of the 55 participating veterinary clinics.
“I think anyone who has an older dog who can participate would jump at the chance.”
deb hannah
Owners must be committed to participating for the entire duration of the study (four years) and must be able to feed their dog a flavored chewable once a day. Half of the dogs in the study will be given an anti-aging drug, and the other half will be given an anti-aging drug. A placebo is administered.
Owners must complete periodic surveys about their dog’s quality of life and take their dog to the clinic for check-ups six times in the first year and twice a year for the next three years. However, there is no cost for these visits). owner).
Future prospects: Royal plans to enroll 1,000 senior dogs in the STAY study, and its first puppy (an 11-year-old whippet named “Boo”) has already been sent to the Dauphin County Animal Hospital in Harrisburg, Pennsylvania. Vaccinations are being administered.
Boo’s owner, Deb Hanna, said of participating in the study, “Maybe someday I can help other dogs, including my young dog.” “It’s very important. I think anyone who has an older dog who can participate would jump at the chance.”

Boo, an 11-year-old whippet, was the first dog to be dosed in the STAY study.
This research may also be useful for people. Dogs are one of the best models of human aging, so Royal’s research could lay the foundation for anti-aging treatments for us too.
“If we succeed, [getting this first-ever aging approval through the veterinary FDA]We want to broadly enable the remaining aging areas if we can, and that’s the real goal,” Loyal CEO Celine Halioua told Freethink.
We look forward to hearing from you! If you have comments about this article or tips for future Freethink stories, please send an email to: tips@freethink.com.