Once-daily acupuncture improved sleep efficiency compared with sham acupuncture in multiple myeloma (MM) patients undergoing autologous hematopoietic stem cell transplantation (HSCT), according to results of a randomized controlled trial. .The results were published in a magazine Acupuncture in medicine.
Although there was a trend toward improvement in wake-up time after sleep onset (WASO), it was not statistically significant between real and sham acupuncture.
In this blinded study (ClinicalTrials.gov identifier: NCT01811862), 63 MM patients were randomized to receive real or sham acupuncture by a licensed acupuncturist for 5 days following chemotherapy. assigned to. Sleep parameters were assessed using an actigraphy-based sleep monitor.
The primary objective of this study was to preliminarily assess the effect of acupuncture on symptom burden in MM patients, with the aim of determining effect sizes for calculating sample sizes for future studies. Previously reported data from this study suggests that acupuncture improves nausea, appetite, sleepiness, and pain. This exploratory analysis evaluated the effect of acupuncture on sleep.
The mean age of patients at baseline was 59 years, and 37% of patients were male. Inpatient chemotherapy was given to 57% of patients.
Sleep efficiency of patients in the true acupuncture group significantly improved, decreasing by 6.70 compared to the sham acupuncture group (95% CI, -13.15 to -0.25; P =.042). The improvement was particularly pronounced in the inpatient setting, with a between-group difference of -9.62 (95% CI, -18.76 to -0.47; 95% CI, -18.76 to -0.47; P =.040).
True acupuncture showed an improvement in WASO, decreasing by 10.95 compared to sham treatment. However, this was not statistically significant (P =.054). There were no significant differences in number of awakenings, total sleep time, or sleep onset latency between treatment groups.
“Our data suggest that true acupuncture may improve certain aspects of sleep, including sleep efficiency and possibly WASO, in MM patients undergoing HSCT,” the authors concluded. I attached it.
Disclosure: One of the study authors declared an affiliation with a biotech, pharmaceutical, or device company. Please refer to the original reference material for a complete list of disclosures.
reference
El-Iskandarani S, Sun L, Lee SQ, et al. Acupuncture improves specific aspects of sleep in hematopoietic stem cell transplant patients: a secondary analysis of a randomized controlled trial. Acupuncture medicine. Published online on July 6, 2023. doi: 10.1177/09645284231181403
